Fatty acid esters
Medchemexpress LLC Octanoyl-L-carnitine-d3 chloride | 1334532-24-9 | MFCD22419179 | 99.9% | 326.87 g/mol | C15H27D3ClNO4 | 5 MG
Octanoyl-L-carnitine-d3 chloride is the deuterium-labeled chloride salt of octanoyl-L-carnitine supplied as a solid stable-isotope standard for analytical and research use. It is intended as an internal standard for LC-MS/MS and GC-MS assays and for metabolic tracing studies of fatty acid and carnitine metabolism. The product is provided in small milligram packs suitable for reference standards and method development.
- Deuterium-labeled internal standard for mass spectrometry assays.
- Provided as the chloride salt for compatibility with aqueous and organic solvents.
- High purity suitable for quantitative analysis.
- Solid, white to off-white appearance for easy handling and storage.
- Supplied in small milligram quantities for reference standard use.
- Useful for metabolic tracing and quantification of acylcarnitines.
Medchemexpress LLC 1-Propanaminium, 3-carboxy-N,N,N-trimethyl-2-(1-oxobutoxy)-, inner salt, (2R)- | 25576-40-3 | 99.9% | 231.29 | 50 MG
Butyrylcarnitine is an endogenous metabolite found in plasma. Elevated levels are associated with abnormalities in lipid and energy metabolism. It can serve as a diagnostic and prognostic indicator for diseases such as heart failure and head and neck cancer. It is for research use only and not sold to patients. Butyrylcarnitine promotes cell proliferation in HN30 cell line in a dose-dependent manner within a certain concentration range and can enhance the proliferation, migration, and invasion abilities of HN30 cells.
- Endogenous metabolite
- Appearance: solid
- Color: white to off-white
- Initial source: endogenous metabolite
- Structure classification: ketones, aldehydes, acids
- Soluble in H2O (≥ 100 mg/mL)
Medchemexpress LLC Stearoylcarnitine | 25597-09-5 | 99.9% | 427.66 | 50 MG
Stearoylcarnitine is a fatty ester lipid molecule and an endogenous metabolite. It can act as a PKC inhibitor and accumulates in β cells, leading to arrest of insulin synthesis and energy deficiency in type 2 diabetes mouse models. It also inhibits lecithin cholesterol acyltransferase (LCAT) in rat and rabbit plasma and serves as a metabolomics biomarker for Parkinson's disease. Additionally, it is a less potent inhibitor of GlyT2.
- Functions as an endogenous metabolite.
- Acts as a PKC inhibitor.
- Accumulates in beta cells, impairing insulin synthesis.
- Inhibits lecithin cholesterol acyltransferase (LCAT) in rat and rabbit plasma.
- Serves as a metabolomics biomarker for Parkinson's disease.
- Less potent inhibitor of GlyT2.
- Impairs mitochondrial energy metabolism in MIN6 cells.
- Alters brain acylcarnitine levels in a mouse model of hypoxic-ischemic brain injury.
Medchemexpress LLC Butyrylcarnitine | 25576-40-3 | 100.0% | 231.29 | 25 MG
Butyrylcarnitine is an endogenous metabolite found in plasma. Elevated levels are associated with abnormalities in lipid and energy metabolism. It can serve as a diagnostic and prognostic indicator for certain diseases, including heart failure and head and neck cancer.
- Endogenous metabolite.
- Associated with lipid and energy metabolism.
- Potential diagnostic and prognostic indicator for heart failure and head and neck cancer.
TARGETMOL CHEMICALS INC Dodecanoylcarnitine 25MG
Also available in 2 mg, 5 mg, 10 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Dodecanoylcarnitine ((-)-Lauroylcarnitine) has been associated with disturbances in fatty acid oxidation, and the use of Dodecanoylcarnitine resulted in an increase in the permeability of salmon calcitonin. Purity 99.72%
Medchemexpress LLC L-Hexanoylcarnitine | 22671-29-0 | 99.9% | 259.34 | 100 MG
L-Hexanoylcarnitine is an acylcarnitine associated with celiac disease and functions as a human endogenous metabolite. It appears as an off-white to light yellow solid.
- Associated with celiac disease
- Functions as a human endogenous metabolite
- Off-white to light yellow solid appearance
- For research use only
Cayman Chemical 3-hydroxy LaurIc AcId 50mg
A hydroxy fatty acid; found in bacteria as well as Pseudosuberites and D. calyx sea sponges; antifungal activity against a panel of seven fungi (MICs = 10-50 μg/ml); partial agonist of GPR84 receptors in vitro (EC50 = 5.24 μM)
eMolecules 29823-18-5 | Ethyl 7-Bromoheptanoate | AA Blocks LLC | MFCD00037103 | 237.137 | C9H17BrO2 | 0.000 | CCOC(=O)CCCCCCBr | 1g | 410180772
Ethyl 7-Bromoheptanoate | AA Blocks LLC | 29823-18-5 | MFCD00037103 | 237.137 | C9H17BrO2 | 0.000 | CCOC(=O)CCCCCCBr | 1g | 410180772
Medchemexpress LLC Monomethyl auristatin E | 474645-27-7 | MFCD09935109 | C68H105N9O15 | 100 MG
Monomethyl auristatin E (MMAE) (GMP) is a tubulin polymerization inhibitor produced using GMP guidelines.
- Produced using GMP guidelines
- Tubulin polymerization inhibitor
- Efficiently released from SGN-35 within CD30+ cancer cells
- Able to exert cytotoxic activity on bystander cells due to membrane permeability
- Sensitizes colorectal and pancreatic cancer cells to IR in a schedule and dose-dependent manner correlating with mitotic arrest
- Radiosensitization evidenced by decreased clonogenic survival and increased DNA double-strand breaks in irradiated cells
- In combination with IR, results in tumor growth delay
- Tumor-targeted ACPP-cRGD-MMAE with IR produces a more robust and significantly prolongs tumor regression in xenograft models